When is hydrogen peroxide produced in cells

The result is that residual bleach makes the entire crime scene produce the typical blue glow, which effectively camouflages any blood stain. And if you want to see a really impressive glow, spray a piece of liver with a luminol test solution. Enter your keywords. Sign-Up Here. How does that happen? A foam forms when bubbles of a gas are trapped in a liquid or solid.

In this case oxygen is generated when hydrogen peroxide breaks down into oxygen and water on contact with catalase, an enzyme found in liver. Is it true that the Beatles wrote a song about LSD? Is it true that you cannot eat polar bear liver? What is Guarana? Facebook Twitter YouTube Instagram. Accessibility Log in. Deletion of the p66 Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet.

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Oxidative stress as a causal factor in differentiation and ageing: a unifying hypothesis. Download references. You can also search for this author in PubMed Google Scholar. Correspondence to Pier Giuseppe Pelicci. Chromosome 21 trisomy. Pier Giuseppe Pelicci's homepage. Reprints and Permissions. Hydrogen peroxide: a metabolic by-product or a common mediator of ageing signals?. Nat Rev Mol Cell Biol 8, — Download citation.

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Our data indicate that Jurkat cells can model both healthy and inflammatory T cells that respond differently to oxidative metabolites such as H2O2. Abstract Hydrogen peroxide H2O2 is well known as a cell damaging agent that is produced during normal cell metabolism of aerobic organisms. Prx actually has a dual role in the process. Its usual job is removing excess hydrogen peroxide from the cells by converting it to water. But if levels get dangerously high -- and Prx needs help -- it becomes inactive in its "converting" job and instead becomes a "signaler," telling the cell to produce or activate other proteins to help remove the excess.

But how does Prx revert back to its usual job and become active again, so that it is available for a new wave of hydrogen peroxide? In , scientists reported that a protein known as sulfiredoxin Srx was involved in the process. The goal of Lowther's team was to use X-ray crystallography to learn exactly what happens. The scientists knew that the repair of Prx would involve it binding with Srx. They also knew that the structure of Prx would need to change because the portion of the molecule that is repaired by Srx is initially hidden when it is in the inactive form.